The museum is mainly dedicated to the Appenzell alpine dairyman culture and the domestic textile industry.

From April 2, 2024, the Appenzell Folklore Museum will unfortunately have to remain temporarily closed to the public. Primarily for financial reasons, operations cannot be maintained for the time being for an indefinite period. During the temporary closure phase, the administration is working intensively with the museum director to find solutions for the museum's continued existence and to develop a concept for the future.